Iron In Osteoporosis

[ironjustice]

Reducing iron accumulation: A potential approach for the prevention and treatment of postmenopausal osteoporosis.
Chen B1, Li GF1, Shen Y1, Huang XI2, Xu YJ1.
Exp Ther Med. 2015 Jul;10(1):7-11. Epub 2015 May 8.

Abstract
Postmenopausal osteoporosis (PMOP) is a systemic bone metabolism disease, characterized by progressive bone loss following menopause and a subsequent increase in fracture risk. Estrogen deficiency as a result of menopause is known to increase bone resorption and accelerate bone loss. Furthermore, postmenopausal women may exhibit iron accumulation, in addition to estrogen deficiency. Elevated iron levels are a risk factor for PMOP in postmenopausal women, and reducing the iron overload has been demonstrated to benefit bone cell metabolism in vitro and improve the bone in vivo by normalizing osteoclastic bone resorption and formation. The identification of hepcidin was a key development in the field of iron metabolism in the previous decade. We hypothesize that hepcidin may aid in the prevention and treatment of PMOP due to its capacity to control body iron stores and its intrinsic effects on osteoblast function. The aim of the current review was to highlight the role of iron accumulation in the pathogenesis of PMOP and to evaluate the possible use of hepcidin as a potential therapy for this condition.

KEYWORDS:
hepcidin; iron; osteoporosis; postmenopause

PMID: 26170904

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/634q5a

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

[Taka]

Post by ironjustice
Reducing iron accumulation: A potential approach for the prevention and treatment of postmenopausal osteoporosis.
Chen B1, Li GF1, Shen Y1, Huang XI2, Xu YJ1.
Exp Ther Med. 2015 Jul;10(1):7-11. Epub 2015 May 8.
Abstract
Postmenopausal osteoporosis (PMOP) is a systemic bone metabolism disease, characterized by progressive bone loss following menopause and a subsequent increase in fracture risk. Estrogen deficiency as a result of menopause is known to increase bone resorption and accelerate bone loss. Furthermore, postmenopausal women may exhibit iron accumulation, in addition to estrogen deficiency. Elevated iron levels are a risk factor for PMOP in postmenopausal women, and reducing the iron overload has been demonstrated to benefit bone cell metabolism in vitro and improve the bone in vivo by normalizing osteoclastic bone resorption and formation. The identification of hepcidin was a key development in the field of iron metabolism in the previous decade. We hypothesize that hepcidin may aid in the prevention and treatment of PMOP due to its capacity to control body iron stores and its intrinsic effects on osteoblast function. The aim of the current review was to highlight the role of iron accumulation in the pathogenesis of PMOP and to evaluate the possible use of hepcidin as a potential therapy for this condition.
hepcidin; iron; osteoporosis; postmenopause
PMID: 26170904
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

We have to invent new ways how to survive the post-reproductive age 'cause the dumb evolution did not think about it...

[Taka]

Post by Taka

Post by ironjustice
Reducing iron accumulation: A potential approach for the prevention and treatment of postmenopausal osteoporosis.
Chen B1, Li GF1, Shen Y1, Huang XI2, Xu YJ1.
Exp Ther Med. 2015 Jul;10(1):7-11. Epub 2015 May 8.
Abstract
Postmenopausal osteoporosis (PMOP) is a systemic bone metabolism disease, characterized by progressive bone loss following menopause and a subsequent increase in fracture risk. Estrogen deficiency as a result of menopause is known to increase bone resorption and accelerate bone loss. Furthermore, postmenopausal women may exhibit iron accumulation, in addition to estrogen deficiency. Elevated iron levels are a risk factor for PMOP in postmenopausal women, and reducing the iron overload has been demonstrated to benefit bone cell metabolism in vitro and improve the bone in vivo by normalizing osteoclastic bone resorption and formation. The identification of hepcidin was a key development in the field of iron metabolism in the previous decade. We hypothesize that hepcidin may aid in the prevention and treatment of PMOP due to its capacity to control body iron stores and its intrinsic effects on osteoblast function. The aim of the current review was to highlight the role of iron accumulation in the pathogenesis of PMOP and to evaluate the possible use of hepcidin as a potential therapy for this condition.
hepcidin; iron; osteoporosis; postmenopause
PMID: 26170904
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

We have to invent new ways how to survive the post-reproductive age 'cause the dumb evolution did not think about it...

When you hit the andropause/menopause and stop having sex, your bones weaken what is called OSTEOPOROSIS and leads to a horrible death in pain. But the intelligent humans invented different approaches to counteract this! E.g.

Monty cured osteoporosis by going EFAD

Tom suggests lowering the iron

Gohde boosts his Moi's manhood by megadoses of VitD3 and VitK

The conventional medicine uses the anabolic steroids (PMID:18830042)

It's all 'bout the reproductive steroid hormones, isn't it? When you can no longer reproduce you don't need the internal skeleton from an evolutionary point of view ... We are all sex machines working overtime and then wonder why we get cancer ....

Taka