Alpha-linolenic Acid In Breast Cancer

[ironjustice]

Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis
European Journal of Nutrition
pp 1-11
First online: 18 November 2015
Marianela Vara-Messler, Maria E. Pasqualini, Andrea Comba, Renata Silva, Carola Buccellati, Annalisa Trenti, Lucia Trevisi, Aldo R. Eynard, Angelo Sala and 2 more

Abstract
Objective
The aim of this study was to determine whether α-linolenic acid (ALA ω-3 fatty acid) enriched diet affects growth parameters when applied to a syngeneic model of mammary carcinoma.
Materials and methods
BALB/c mice were divided and fed with: 1) a chia oil diet, rich in ALA or 2) a corn oil diet, rich in linoleic acid (LA ω-6 fatty acid). Mice were subcutaneously inoculated with a tumor cell line LM3, derived from a murine mammary adenocarcinoma.
Results
After 35 days, tumor incidence, weight, volume and metastasis number were lower in the ALA-fed mice, while tumor latency time was higher, and the release of pro-tumor metabolites derived from ω-6 fatty acids decreased in the tumor. Compared to the control group, a lower number of mitosis, a higher number of apoptotic bodies and higher T-lymphocyte infiltration were consistently observed in the ALA group. An ALA-rich diet decreased the estrogen receptor (ER) α expression, a recognized breast cancer promotor while showing an opposite effect on ERβ in tumor lysates.
Conclusion
These data support the anticancer effect of an ALA-enriched diet, which might be used as a dietary strategy in breast cancer prevention.

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/634q5a

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

[Taka]

Post by ironjustice
Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis
European Journal of Nutrition
pp 1-11
First online: 18 November 2015
Marianela Vara-Messler, Maria E. Pasqualini, Andrea Comba, Renata Silva, Carola Buccellati, Annalisa Trenti, Lucia Trevisi, Aldo R. Eynard, Angelo Sala and 2 more
Abstract
Objective
The aim of this study was to determine whether α-linolenic acid (ALA ω-3 fatty acid) enriched diet affects growth parameters when applied to a syngeneic model of mammary carcinoma.
Materials and methods
BALB/c mice were divided and fed with: 1) a chia oil diet, rich in ALA or 2) a corn oil diet, rich in linoleic acid (LA ω-6 fatty acid). Mice were subcutaneously inoculated with a tumor cell line LM3, derived from a murine mammary adenocarcinoma.
Results
After 35 days, tumor incidence, weight, volume and metastasis number were lower in the ALA-fed mice, while tumor latency time was higher, and the release of pro-tumor metabolites derived from ω-6 fatty acids decreased in the tumor. Compared to the control group, a lower number of mitosis, a higher number of apoptotic bodies and higher T-lymphocyte infiltration were consistently observed in the ALA group. An ALA-rich diet decreased the estrogen receptor (ER) α expression, a recognized breast cancer promotor while showing an opposite effect on ERβ in tumor lysates.
Conclusion
These data support the anticancer effect of an ALA-enriched diet, which might be used as a dietary strategy in breast cancer prevention.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

No need for the "scientists" to tell us this, too late for them to realize. This has been already known as the Budwig Diet long before they were born... When Gohde is taken down by his prostate his Moi will run for this cure ;-)

http://www.budwigcenter.com/