Discussion:
A recent review of vitamin c "needs" among the healthy
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d***@gmail.com
2017-07-24 12:21:09 UTC
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40 milligrams is dead wrong. Early research on the topic showed a reduction of visible blood abnormalities by East Bloc researchers by way of 120 milligrams among chemical/industrial workers. And recent research reveals similar findings.
Let see if the moderator will be honest enough to permit comment with me quoting an abstract and providing a link to the full paper.
Below is a fair use quote:
"Nutrients. 2017 May 16;9(5). pii: E503. doi: 10.3390/nu9050503.
Emerging Evidence on Neutrophil Motility Supporting Its Usefulness to DefineVitamin C Intake Requirements.
(snip)

"Establishing intake recommendations for vitamin C remains a challenge, as no suitable functional parameter has yet been agreed upon. In this report, we review the emerging evidence on neutrophil motility as a possible marker of vitamin Crequirements and put the results in perspective with other approaches. A recent in vitro study showed that adequate levels of vitamin C were needed for this functions to work optimally when measured as chemotaxis and chemokinesis. In a human study, neutrophil motility was optimal at intakes ≥250 mg/day.Interestingly, a Cochrane review showed a significant reduction in the duration of episodes of the common cold with regular vitamin C intakes in a similar range.Additionally, it was shown that at a plasma level of 75 µmol/L, which is reached with vitamin C intakes ≥200 mg/day, incidences of cardiovascular disease were lowest. This evidence would suggest that daily intakes of 200 mg vitamin C might be advisable for the general adult population, which can be achieved by means of a diverse diet. However, additional studies are warranted to investigate the usefulness of neutrophil motility as a marker of vitamin C requirements.
(snip)PMID: 28509882 "

www.ncbi.nlm.nih.gov/pmc/articles/PMC5452233/

The above post was to the link below here but the author or paper will likely reject it.
http://www.express.co.uk/life-style/health/831598/supplements-vitamins-nutrients-vitamin-C-stomach-pain-farting-symptoms
Taka
2017-07-25 04:58:11 UTC
Permalink
Post by d***@gmail.com
40 milligrams is dead wrong. Early research on the topic showed a reduction of visible blood abnormalities by East Bloc researchers by way of 120 milligrams among chemical/industrial workers. And recent research reveals similar findings.
Let see if the moderator will be honest enough to permit comment with me quoting an abstract and providing a link to the full paper.
"Nutrients. 2017 May 16;9(5). pii: E503. doi: 10.3390/nu9050503.
Emerging Evidence on Neutrophil Motility Supporting Its Usefulness to DefineVitamin C Intake Requirements.
(snip)
"Establishing intake recommendations for vitamin C remains a challenge, as no suitable functional parameter has yet been agreed upon. In this report, we review the emerging evidence on neutrophil motility as a possible marker of vitamin Crequirements and put the results in perspective with other approaches. A recent in vitro study showed that adequate levels of vitamin C were needed for this functions to work optimally when measured as chemotaxis and chemokinesis. In a human study, neutrophil motility was optimal at intakes ≥250 mg/day.Interestingly, a Cochrane review showed a significant reduction in the duration of episodes of the common cold with regular vitamin C intakes in a similar range.Additionally, it was shown that at a plasma level of 75 µmol/L, which is reached with vitamin C intakes ≥200 mg/day, incidences of cardiovascular disease were lowest. This evidence would suggest that daily intakes of 200 mg vitamin C might be advisable for the general adult population, which can be achieved by means of a diverse diet. However, additional studies are warranted to investigate the usefulness of neutrophil motility as a marker of vitamin C requirements.
(snip)PMID: 28509882 "
www.ncbi.nlm.nih.gov/pmc/articles/PMC5452233/
The above post was to the link below here but the author or paper will likely reject it.
http://www.express.co.uk/life-style/health/831598/supplements-vitamins-nutrients-vitamin-C-stomach-pain-farting-symptoms
Animals who manufacture VitC themselves have much higher blood conc. of it! E.g. dog's liver make VitC in the order of grams on daily basis... Humans (the ice apes) have evolved reduced need for VitC substituting it with e.g. cholesterol to plug the arteries etc.
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